For a bedroom, run the Dry 4000 in Night mode — it dims the unit's display and reduces fan speed to minimise disturbance while still working through the night, which UK health guidance generally recommends to keep humidity in the 45-55% range and reduce dust mites and mould spores.
For drying laundry, switch to Laundry mode and position the unit close to a clothes airer in a closed room, the same principle that applies to every compressor dehumidifier on this site — a sealed space means the extracted moisture isn't constantly replaced by humid air from elsewhere in the house.
For day-to-day use across a mid-size room, Auto mode is the simplest option: set it and the Dry 4000 will run until it hits its target humidity level, then cycle on and off to maintain it, similar in principle to the smart humidity modes on the Meaco range. Because the 2.5-litre tank is relatively small for a 16L/day unit, connecting the drainage hose is worth doing if you want to leave it running unattended for more than a day, particularly in a genuinely damp room where it's extracting near its full capacity.
For persistent black mould or condensation on a specific wall or window, position the Dry 4000 as close to that spot as practical while still allowing airflow on all sides, and run Auto mode continuously for the first week or two rather than switching it off once the room feels dry — mould spores and the underlying damp in plaster or wood can take longer to clear than the air itself.
If you're moving the Dry 4000 between rooms regularly — say, from a bedroom overnight to a living room during the day — give it a few minutes after moving before judging its noise level and performance in the new spot; like most compressor units, it needs a short settling period after being relocated before the humidity sensor gives an accurate reading.